Specimen type

Aspergillus galactomannan antigen ELISA

Optimal time of specimen collection

No specific time, first clinical indication of invasive aspergillosis

Correct specimen type and method of collection

Clotted blood, serum, BAL, urine. EDTA blood is not suitable.

Quantity and number of specimens

Serum 700ml minimum or 5 ml clotted blood, prospective screening twice weekly

Laboratory analysis

Platelia ELISA for Aspergillus galactomannan circulating antigen in serum and other body fluids. Results reported as Negative, Positive (report includes cut-off value). Specificity of the test is improved if two or more consecutive specimens are positive.

Transport

As per Microbiology guidelines

Turnaround time

1-2 days

Indicative cost per sample

£46